4H-1-Benzopyran-4-one, 2,3-dihydro-7-hydroxy-2-(4-hydroxy-2-methoxyphenyl)-5-methoxy-8-[(2R)-5-methyl-2-(1-methylethenyl)-4-hexen-1-yl]-, (2S)-
2'-O-Methylkurarinone
CAS: 270249-38-2
Molecular Formula: C27H32O6
4H-1-Benzopyran-4-one, 2,3-dihydro-7-hydroxy-2-(4-hydroxy-2-methoxyphenyl)-5-methoxy-8-[(2R)-5-methyl-2-(1-methylethenyl)-4-hexen-1-yl]-, (2S)- - Names and Identifiers
| Name | 2'-O-Methylkurarinone |
| Synonyms | 2'-O-Methylkurarinone (2S)-2-Methoxykurarinone Kurarinone, 2'-O-methyl- (2S)-2-METHOXYKURARINONE (2S)-7-hydroxy-2-(4-hydroxy-2-methoxyphenyl)-5-methoxy-8-[(2R)-5-methyl-2-prop-1-en-2-ylhex-4-enyl]-2,3-dihydrochromen-4-one 4H-1-Benzopyran-4-one, 2,3-dihydro-7-hydroxy-2-(4-hydroxy-2-methoxyphenyl)-5-methoxy-8-[(2R)-5-methyl-2-(1-methylethenyl)-4-hexen-1-yl]-, (2S)- |
| CAS | 270249-38-2 |
4H-1-Benzopyran-4-one, 2,3-dihydro-7-hydroxy-2-(4-hydroxy-2-methoxyphenyl)-5-methoxy-8-[(2R)-5-methyl-2-(1-methylethenyl)-4-hexen-1-yl]-, (2S)- - Physico-chemical Properties
| Molecular Formula | C27H32O6 |
| Molar Mass | 452.54 |
| Density | 1.171±0.06 g/cm3(Predicted) |
| Melting Point | 112-115℃ |
| Boling Point | 643.6±55.0 °C(Predicted) |
| pKa | 7.50±0.40(Predicted) |
| Storage Condition | 2-8°C |
4H-1-Benzopyran-4-one, 2,3-dihydro-7-hydroxy-2-(4-hydroxy-2-methoxyphenyl)-5-methoxy-8-[(2R)-5-methyl-2-(1-methylethenyl)-4-hexen-1-yl]-, (2S)- - Reference Information
| Plant Source: | Sophora flavescens |
| biological activity | (2S)-2 '-Methoxykurarinone is a compound isolated from the root of Sophora flavescens Ait, it has anti-inflammatory, antipyretic, anti-diabetic and anti-tumor effects. (2S)-2 '-Methoxykurarinone inhibits osteoclast formation and bone resorption by down-regulating RANKL signaling. (2S)-2 '-Methoxykurarinone has cytotoxic activity against human myeloid leukemia HL-60 cells. |
Last Update：2024-04-09 21:54:55
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View History
4H-1-Benzopyran-4-one, 2,3-dihydro-7-hydroxy-2-(4-hydroxy-2-methoxyphenyl)-5-methoxy-8-[(2R)-5-methyl-2-(1-methylethenyl)-4-hexen-1-yl]-, (2S)-
3-[(2-Bromo-4-isopropylphenoxy)methyl]pyrrolidinehydrochloride
庚烯磷
4-[4-(3-CHLOROPHENYL)PIPERAZINO]-6-(METHOXYMETHYL)-2-PHENYLPYRIMIDINE
4-((4-cyano-1H-pyrazol-1-yl)methyl)benzene-1-sulfonyl fluoride4-((4-cyano-1H-pyrazole-1-yl)methyl)benzene-1-sulphonyl fluoride
琥珀酸钡
Tetrabutylphosphonium trifluorotris(pentafluoroethyl)phosphate
Estr-4-en-3-one,17-hydroxy-,(22β)-
3-METHYLPYRIDINE-2-BORONIC ACID PINACOL ESTER
PidotiMod Diketopiperazine-6-propanoic Acid
3-[(2-Bromo-4-isopropylphenoxy)methyl]pyrrolidinehydrochloride
庚烯磷
4-[4-(3-CHLOROPHENYL)PIPERAZINO]-6-(METHOXYMETHYL)-2-PHENYLPYRIMIDINE
4-((4-cyano-1H-pyrazol-1-yl)methyl)benzene-1-sulfonyl fluoride4-((4-cyano-1H-pyrazole-1-yl)methyl)benzene-1-sulphonyl fluoride
琥珀酸钡
Tetrabutylphosphonium trifluorotris(pentafluoroethyl)phosphate
Estr-4-en-3-one,17-hydroxy-,(22β)-
3-METHYLPYRIDINE-2-BORONIC ACID PINACOL ESTER
PidotiMod Diketopiperazine-6-propanoic Acid